Research & Development Scientist at PathoGene, Inc.

General Summary:

Working closely with our executive team and corporate advisors, the R&D scientist will help us design and validate our pipeline for DNA extraction, NGS library preparation, and sequencing. This position requires a solid working knowledge of common lab protocols, the ability to problem-solve, and a detail-oriented work style. This position will require an individual to think critically about designing and optimizing a pipeline. Work will also include applying and using a robotic pipetting apparatus that automates workflows developed by the candidate.

Duties and Responsibilities:

• The candidate will process human biosamples for sequencing (end-to-end).
• Protocols include but are not limited to DNA/RNA depletion, DNA extraction, NGS library preparation, and sequencing.
• The majority of the protocols will be direct applications from commercial kits. On occasion, we will be designing custom protocols and experiments.
• The candidate must document and report experimental results, troubleshoot equipment, order supplies, perform general lab housekeeping, and maintain safety records.
• The candidate will regularly collaborate with an on-site medical device programmer and report to the chief science officer.

Minimum Qualifications:

• Bachelor’s degree in biology, chemistry, or related field required.
• Experience with laboratory research techniques is necessary with a willingness to problem-solve.

Skills and abilities:

• Must be able to work independently without guidance.
• Strong communication and interpersonal skills when working with our team are a must.
• Python programming experience is preferred but not required.

Technical qualifications:

• DNA/RNA depletion, DNA extraction, library preparation, sequencing, PCR, and other common lab protocols.
• Independently conduct research while documenting and compiling results.

Physical Requirements:

• Standing for extended periods.
• Lifting lab equipment.
• The dexterity required to manipulate objects and perform labs.

About Us:

PathoGene, Inc. is a private, seed-stage precision MedTech startup headquartered in Los Angeles, with R&D operations located in Monrovia, California. We are developing a sample-to-answer in vitro diagnostic medical device that detects and identifies all known microscopic human pathogens along with antimicrobial resistance profiles. To do this, we leverage robotic automation, third-generation DNA and RNA sequencing, and cloud computing technologies to report notifiable diseases to care providers and disease surveillance systems in real-time.

Our goal is to deliver the necessary diagnostic tools for doctors and medical staff to make optimal treatment decisions that can ultimately improve public health as a whole, and we believe that our sample-to-answer technology can become the global standard of care for diagnosing infectious diseases.

‍